Minnows Darlington Mowden Park plan to try and enjoy every minute of their David and Goliath Tetley's Bitter Cup clash at Harlequins tomorrow.

The North One leaders, fourth round conquerors of Rosslyn Park, will be roared on by around 500 travelling supporters at The Stoop.

And rugby director John Parkinson says Mowden Park will relish the biggest day in their history, whatever the outcome.

"We are looking forward to it enormously," Parkinson said.

There is a sense of great excitement and trepidation. It's a daunting prospect going down there, but the bottom line is that everyone enjoys it and has a day to remember.

"Quality of performance is more important to us than the result, and it will be fantastic to have so many people at The Stoop lending their support."

Mowden Park's long unbeaten league record came to an end at Chester last weekend, and given that Quins demolished Thurrock 88-0 in round four, the formbook suggests another landslide home win.

"We would see it as a marvellous compliment if Quins send out their strongest available side against us," Parkinson added.

"But always remember that sport has been littered with some massive upsets down the years."

While Mowden Park relish the big time, Wasps and Newcastle will be locked in a repeat of last season's cup final at Loftus Road.

Both clubs are striving for Premiership consistency, but know that this year's cup winners are guaranteed a prized Heineken Cup place next term as automatic qualifiers.

Wasps refuse to press any panic buttons despite successive European and Premiership losses against Llanelli, Bath and Leicester, yet realise the importance of a successful cup run.

"The biggest problem in recent games has been ourselves we are our own worst enemy sometimes," said rugby director Nigel Melville.

"We've got to stop giving away cheap penalties to top-class goalkickers, but a lot of positive things have materialised from the past few matches, and we will look to build on that."

Wasps are without England lock Simon Shaw, who suffered a bang on the knee against Leicester in midweek, but Newcastle must cope minus long-term injury victims Peter Walton and Ross Nesdale, while running fitness checks over several other players.

Bristol and Sale meet at the Memorial Stadium four days after their scheduled league fixture was postponed because of fog with Bristol red-hot favourites to progress.

Sale full-back Jim Mallinder and Alex Sanderson, who would both have missed Wednesday night's game, could return from injury.