- Floyd Mayweather Jnr v Miguel Cotto
Khan tips Mayweather to outclass Cotto
Mayweather has only fought at the weight once before - conquering Oscar De La Hoya in 2007 - but despite a lack of experience, few are siding against the unbeaten American.
The last time Cotto walked in such celebrated company was when he was stopped in the 12th round by Manny Pacquiao in 2009 - and Khan expects the Puerto Rican to fall short again at the highest level.
"I reckon Mayweather wins against Cotto, but will be a skilful match," Khan said on Twitter. "Mayweather's speed will be an upside, but I like how tight and composed Cotto is."
Khan has said he is looking to emulate Mayweather when he takes to the ring against WBA and IBF light-welterweight supremo Lamont Peterson for a second time during May.