Anthony Watson (right) replaces the injured Semesa Rokoduguni © Getty Images

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England have made just one change ahead of Saturday's game against the Springboks at Twickenham.

With Semesa Rokoduguni ruled out due to a hip injury, his Bath team-mate Anthony Watson is handed his first Test start on the wing where he will face the unenviable task of trying to contain Bryan Habana. In the pack, Tom Wood was an injury doubt but he retains his place at blindside while Marland Yarde is added to the bench to cover the back three.

Dylan Hartley and Courtney Lawes suffered concussions against New Zealand last weekend but both have completed the graduated return to play protocol and start in the pack. At half-back, Danny Care wins his 50th cap.

England in must-win territory

• I am always asked how good the current England team is compared to our 2003 crop and it is a difficult question to answer. They are in different places but the one thing which binds both is the necessity to win. It runs through the sport but Saturday's game against the Springboks now falls into the 'must-win' category for England. They have to re-establish Twickenham as a scary place for the southern hemisphere sides to visit.
• England have the tools to win these big games, but they must really believe they can do it. The All Blacks were there for the taking but England struggled to cope with their direct running. They missed an opportunity to put down a marker; that match was a chance to really show how good they are. The players must get bored of looking at all the positive stats they get when they face the All Blacks - the lineout was great etc. - but it is still a defeat. They have to learn the key lessons from that match ahead of this weekend and all the talk this week has been about game management.
• Read Phil Vickery's column here

"Anthony has been pushing hard for a while and has been in impressive form for Bath and in training with us," Lancaster said. "It was great that he got on against New Zealand and we feel he is ready to start. Equally, it's good to have Marland back in the matchday 23. Congratulations to Danny Care who will be winning his 50th cap. It'll be a special moment for him and I am sure he will rise to the occasion."

England will hope to bounce back against South Africa on Saturday after falling to a 24-21 loss to New Zealand last weekend. But they will not have it easy against the Springboks who have not lost to England since 2006.

"I know the players are looking forward to the challenge," Lancaster added. "South Africa have quality and experience across the park and it will be a big test for us."

England:

Mike Brown, Anthony Watson, Brad Barritt, Kyle Eastmond, Jonny May, Owen Farrell, Danny Care; Joe Marler, Dylan Hartley, Dave Wilson, Dave Attwood, Courtney Lawes, Tom Wood, Chris Robshaw (captain), Billy Vunipola

Replacements: Rob Webber, Matt Mullan, Kieran Brookes, George Kruis, Ben Morgan, Ben Youngs, George Ford, Marland Yarde