Quaife-Hobbs ensured he stood out from an early age by winning the 2005 BRSCC T-Cars Championship to become the youngest ever winner of an MSA-sanctioned championship.
In 2007 Quaife-Hobbs made the switch to single seaters and the Formula BMW category, finishing his debut campaign in 10th place in the championship. He then moved in to Formula Renault, securing a podium in his third race before switching to the Formula Three Euro Series in 2010 and scoring a best result of fifth place in the opening two rounds before opting to race in GP3.
His first season in GP3 resulted in one podium, but he improved the following year to win once and finish on the podium twice en-route to joint fourth in the championship standings. He also earned an F1 test for Virgin in Abu Dhabi before dominating the Auto GP World Series in 2012, with five wins and ten podiums en-route to the title.
Quaife-Hobbs will move in to GP2 in 2013 with Dutch team MP Motorsport.