Britain's hopes ended in Edgbaston
Britain's last hope Johanna Konta suffered defeat in her second round match with Aleksandra Wozniak at the Aegon Classic in Edgbaston.
Qualifier Wozniak saved three match points against another Brit, Heather Watson, in the opening round in Birmingham but eased through to the third with a 6-4 6-2 against Konta.
Sam Stosur made it through to the third round as she demolished the American Christina McHale 6-1 6-3.
The No.2 seed, who has traditionally struggled on grass, dominated her opponent in all departments to set up an all-Australian third round with Casey Dellacqua, who saw off the challenge of Varvara Lepchenko to advance 6-4 6-3.
"It was pretty clean all round." Stosur said. "There are a couple of little things I would like to try and tidy up, but overall I was really happy with the way I played out there and the way I felt. So for my first match on grass, I'm pretty happy."
The Australian pair will be joined in the last-16 by third seed Sloane Stephens, who dispatched former French Open champion Francesca Schiavone in straight sets to win 6-2 6-4. The Italian probed without ever threatening the young American, who looked composed throughout.
"I'm always happy to be back in Birmingham," Stephens said. "I love everyone here. It's just like reuniting with family. Obviously I'm playing on grass, which I love, so it's a very comfortable place."
Elsewhere, it was not such good news for No.5 seed Lucie Safarova, who was knocked out in three sets by the unseeded Barbora Zahlavova Strycova 6-3 3-6 7-5.
Kimiko Date-Krumm edged past twelfth seed Monica Puig 2-6 6-4 7-6(7), while Timea Babos sent eleventh seed Madison Keys crashing out 6-2 6-1.