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Cormier: Only Dos Santos can beat Velasquez
Cormier currently competes at heavyweight himself and made a successful UFC debut by out-pointing Frank Mir in a recent match-up.
However, while team-mate Velasquez is champion Cormier has no designs on the heavyweight title. It is expected he will soon move to the 205lb weight class to seek out Jon Jones.
Those plans do not stop him forming an opinion of Velasquez's rivals though, and ahead of UFC 160 - which sees the champion face Antonio Silva, Cormier insists only Dos Santos offers a threat to Velasquez.
"They're not beating Cain. They're not good enough," he told Bleacher Report.
"I'm telling you right now I think they're great, I think Junior Dos Santos is great. I think Junior Dos Santos has the best chance of beating Cain.
"But the rest, they're not beating him. They're not good enough. It's about as honest as I can be with you - they're not good enough to beat him."
Dos Santos and Velasquez have already met twice, with the former taking the first bout in under two minutes, before the latter dominated the second encounter to regain his belt.