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New South Wales Waratahs have ruled Tatafu Polota-Nau out of the Super Rugby match against Western Force on Saturday amid growing concerns for the Wallabies hooker's long-term health and future in the game.

Polota-Nau was concussed early in the Waratahs' victory over the Brumbies last Friday, little more than a month after missing several weeks of action because of a head knock suffered at training. The 29-year-old has a history of head-related injuries and he said earlier this week that he may have to consider hanging up the boots if he was concussed again.

"There's more to life than just rugby," Polota-Nau said.

Waratahs assistant coach Nathan Grey confirmed on Wednesday that Polota-Nau would miss the trip to Perth, and would be monitored carefully before being cleared for any comeback.

"He's out, he's no good," Grey said.

Super Rugby's governing body SANZAR beefed up its laws around concussions this year, moving in line with World Rugby protocols, with independent doctors given more power to prevent players from returning to the field after undergoing sideline testing.

Concussed players also have to pass a series of strict tests the following week before being allowed to resume playing.

"It's a good system," Grey said.

Polota-Nau has also undergone a series of brain scans this year, and long-time Waratahs and Wallabies team-mate Benn Robinson applauded the 50-Test veteran for taking his health seriously.

"For me, I'm more worried about a mate because we've seen players retire in recent years," Robinson said. "You can look at some of the many studies coming out of the NFL and players committing suicide post their careers. It's a scary thing. So for me, it's a concern for a mate because I've been playing with Taf since I was 15 and to see, I don't know, like 12 concussions for him in recent years, it's a major concern."

Feeling like he has "unfinished business in rugby", Polota-Nau said a long break or retirment would be a wrench. But Robinson said Polota-Nau had to be careful.

"It comes back to player welfare and making sure he's not putting himself in an adverse position for the rest of his life," Robinson said. "We're here [as players] for luckily 10 or 12 years. We've still got a lot of time left in the world, so you don't want to be compromised for the rest of your life."

Waratahs head coach Michael Cheika is yet to name his side to tackle the Force, but Grey said that Tolu Latu had already proven himself more than capable of replacing Polota-Nau.

"He's been outstanding. Even with Tatafu being fit the week prior to the Brumbies game, Tolu was getting picked in front of him. So we've got absolute confidence in him to be really able to contribute to the way we play. He's got a great skill set, his set piece is excellent and he's someone who is really contributing to the team in a positive way."