May 1, 1988 Autodromo Enzo e Dino Ferrari | Lap distance 5.040 km
| Pos | Points | No | Driver | Car | Engine | Tyres | Laps | Race Time | Delay | Qualifying | Fastest Lap | |||
| 1 | 9 | 12 | Ayrton Senna (BRA) | McLaren MP4-4 | Honda RA168-E | Goodyear | 60 | 1.000000.264 | 1 | 7.000000.148 | 2 | 9.000000.815 | (56) | |
| 2 | 6 | 11 | Alain Prost (FRA) | McLaren MP4-4 | Honda RA168-E | Goodyear | 60 | 3.000000.598 | +2.000000.334 | 2 | 7.000000.919 | 1 | 9.000000.685 | (53) |
| 3 | 4 | 1 | Nelson Piquet (BRA) | Team Lotus 100T | Honda RA168-E | Goodyear | 59 | 8.000000.824 | +1 lap | 3 | 0.000 | 9 | 2.000000.414 | (57) |
| 4 | 3 | 20 | Thierry Boutsen (BEL) | Benetton B188 | Ford Cosworth DFR | Goodyear | 59 | 9.000000.373 | +1 lap | 8 | 1.000000.414 | 7 | 2.000000.317 | (55) |
| 5 | 2 | 28 | Gerhard Berger (AUT) | Ferrari F1/87-88C | Ferrari 156/88 | Goodyear | 59 | 0.000 | +1 lap | 5 | 0.000 | 3 | 1.000000.394 | (56) |
| 6 | 1 | 19 | Alessandro Nannini (ITA) | Benetton B188 | Ford Cosworth DFR | Goodyear | 59 | 5.000000.735 | +1 lap | 4 | 0.000 | 6 | 2.000000.034 | (57) |
| 7 | 18 | Eddie Cheever (USA) | Arrows A10B | Megatron | Goodyear | 59 | 5.000000.119 | +1 lap | 7 | 1.000000.300 | 5 | 2.000000.017 | (49) | |
| 8 | 2 | Satoru Nakajima (JPN) | Team Lotus 100T | Honda RA168-E | Goodyear | 59 | 1.000000.638 | +1 lap | 12 | 1.000000.647 | 12 | 3.000000.209 | (58) | |
| 9 | 17 | Derek Warwick (GBR) | Arrows A10B | Megatron | Goodyear | 58 | 3.000000.299 | +2 laps | 14 | 2.000000.483 | 18 | 4.000000.056 | (41) | |
| 10 | 14 | Philippe Streiff (FRA) | AGS JH23 | Ford Cosworth DFZ | Goodyear | 58 | 6.000000.274 | +2 laps | 13 | 2.000000.013 | 19 | 4.000000.226 | (41) | |
| 11 | 24 | Luis Perez-Sala (ESP) | Minardi M188 | Ford Cosworth DFZ | Goodyear | 58 | 1.000000.547 | +2 laps | 18 | 3.000000.239 | 17 | 4.000000.014 | (57) | |
| 12 | 29 | Yannick Dalmas (FRA) | Lola LC88 | Ford Cosworth DFZ | Goodyear | 58 | 5.000000.587 | +2 laps | 19 | 3.000000.374 | 14 | 3.000000.623 | (56) | |
| 13 | 6 | Riccardo Patrese (ITA) | Williams FW12 | Judd CV | Goodyear | 58 | 1.000000.980 | +2 laps | 6 | 0.000 | 10 | 2.000000.758 | (32) | |
| 14 | 3 | Jonathan Palmer (GBR) | Tyrrell 017 | Ford Cosworth DFZ | Goodyear | 58 | 3.000000.881 | +2 laps | 23 | 3.000000.972 | 15 | 3.000000.660 | (54) | |
| 15 | 15 | Mauricio Gugelmin (BRA) | March 881 | Judd CV | Goodyear | 58 | 4.000000.672 | +2 laps | 20 | 3.000000.448 | 16 | 3.000000.890 | (55) | |
| 16 | 23 | Adrián Campos (ESP) | Minardi M188 | Ford Cosworth DFZ | Goodyear | 57 | 5.000000.933 | +3 laps | 22 | 3.000000.903 | 22 | 5.000000.708 | (39) | |
| 17 | 30 | Philippe Alliot (FRA) | Lola LC88 | Ford Cosworth DFZ | Goodyear | 57 | 2.000000.950 | +3 laps | 15 | 2.000000.712 | 11 | 2.000000.863 | (56) | |
| 18 | 27 | Michele Alboreto (ITA) | Ferrari F1/87-88C | Ferrari 156/88 | Goodyear | 54 | 0.000 | +6 laps | 10 | 1.000000.520 | 4 | 1.000000.864 | (50) | |
| Not classified | ||||||||||||||
| -- | 33 | Stefano Modena (ITA) | Euro Brun ER-188 | Ford Cosworth DFZ | Goodyear | 52 | 8.000000.066 | 26 | 4.000000.782 | 13 | 3.000000.214 | (49) | ||
| Retirement | ||||||||||||||
| gearbox | 4 | Julian Bailey (GBR) | Tyrrell 017 | Ford Cosworth DFZ | Goodyear | 48 | 5.000000.810 | 21 | 3.000000.874 | 20 | 5.000000.288 | (48) | ||
| engine | 5 | Nigel Mansell (GBR) | Williams FW12 | Judd CV | Goodyear | 42 | 1.000000.222 | 11 | 1.000000.635 | 8 | 2.000000.372 | (35) | ||
| fuel system | 31 | Gabriele Tarquini (ITA) | Coloni FC-188 | Ford Cosworth DFZ | Goodyear | 40 | 4.000000.130 | 17 | 3.000000.236 | 21 | 5.000000.395 | (31) | ||
| gearbox | 36 | Alex Caffi (ITA) | Dallara BMS-188 | Ford Cosworth DFZ | Goodyear | 18 | 1.000000.447 | 24 | 4.000000.204 | 24 | 6.000000.285 | (17) | ||
| gearbox | 9 | Piercarlo Ghinzani (ITA) | Zakspeed 881 | Zakspeed 881 | Goodyear | 16 | 5.000000.424 | 25 | 4.000000.567 | 23 | 6.000000.122 | (14) | ||
| gearbox | 16 | Ivan Capelli (ITA) | March 881 | Judd CV | Goodyear | 2 | 5.000000.782 | 9 | 1.000000.519 | 25 | 7.000000.842 | (2) | ||
| suspension | 22 | Andrea de Cesaris (ITA) | Rial ARC-01 | Ford Cosworth DFZ | Goodyear | 0 | 16 | 3.000000.037 | ||||||
| Disqualified | ||||||||||||||
| -- | 21 | Nicola Larini (ITA) | Osella FA1L | Osella 890T | Goodyear | 0 | ||||||||
| Not qualified | ||||||||||||||
| -- | 32 | Oscar Larrauri (ARG) | Euro Brun ER-188 | Ford Cosworth DFZ | Goodyear | 5.000000.077 | ||||||||
| -- | 26 | Stefan Johansson (SWE) | Ligier JS31 | Judd CV | Goodyear | 5.000000.654 | ||||||||
| -- | 25 | René Arnoux (FRA) | Ligier JS31 | Judd CV | Goodyear | 6.000000.123 | ||||||||
| -- | 10 | Bernd Schneider (GER) | Zakspeed 881 | Zakspeed 881 | Goodyear | 6.000000.218 | ||||||||
